A novel DNA-templated click chemistry strategy for fluorescent detection of copper(II) ions.
نویسندگان
چکیده
A novel fluorescent strategy has been developed for sensitive turn-on detection of Cu(2+) based on high efficiency of DNA-templated organic synthesis, great specificity of alkyne-azide click reaction to the catalysis of copper ions and the sequential strand displacement for signal transduction.
منابع مشابه
Three-Component and Click Strategy for Synthesis of β-Hydroxy 1,4-Disubstituted 1,2,3-Triazoles Derivatives Catalyzed by 1,4-Dihydroxyanthraquinone-copper(II) Complex onto Nano AlPO4
In this work, copper(II) heterogeneous nanocatalyst supported on modified AlPO4 (Cu(II)-DA@Nano AlPO4) was used for the synthesis of some biological active heterocyclic molecules, particularly for the efficient conversion of a wide range of non-activated terminal alkynes to β-hydroxy 1,4-disubstituted 1,2,3-triazolethrough a three-component “click” reaction at room temperature in water. The reg...
متن کاملRandom dsDNA-templated formation of copper nanoparticles as novel fluorescence probes for label-free lead ions detection.
A simple label-free method for the detection of Pb(2+) ions with high selectivity and sensitivity has been developed by using random double-strand DNA-templated formation of copper nanoparticles as novel fluorescence probes in aqueous solution.
متن کاملInhibition of dsDNA-templated copper nanoparticles by pyrophosphate as a label-free fluorescent strategy for alkaline phosphatase assay.
On the basis of the inhibition of double strand DNA (dsDNA)-templated fluorescent copper nanoparticles (CuNPs) by pyrophosphate (PPi), a novel label-free turn-on fluorescent strategy to detect alkaline phosphatase (ALP) under physiological conditions has been developed. This method relies on the strong interaction between PPi and Cu(2+), which would hamper the effective formation of fluorescent...
متن کاملAn Electrochemical Sensor Based on Novel Ion Imprinted Polymeric Nanoparticles for Selective Detection of Lead Ions
In this study, the novel surface ion-imprinted polymer (IIP) particles were prepared and applied as a electrode modifier in stripping voltammetric detection of lead(II) ion. A carbon paste electrode (CPE) modified with IIP nanoparticles and multi-walled carbon nanotubes (MWCNTs) was used for accumulation of toxic lead ions. Various factors that govern on electrochemical signals including carbon...
متن کاملDNA interaction and antimicrobial studies of novel copper (II) complex having ternary Schiff base
A novel ternary Schiff base ligand (HL) of ONO type and its copper (II) complex weresynthesised using 2-aminophenol and o-acetoacetotoluidide. They have been characterised by theusual analytical and spectral methods. The interaction of the complex with calf-thymus (CT)DNA has been investigated by UV-Vis, viscosity measurement, cyclic voltammetry anddifferential pulse voltammetry studies. The re...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Chemical communications
دوره 48 2 شماره
صفحات -
تاریخ انتشار 2012